The Eighth Street Baptist Church is significant in the areas of Black Ethnic Heritage and Social History for its extended association with one of Pueblo's oldest Black church congregations where social events, programs, and activities were held in the late-nineteenth and twentieth centuries to support and uplift the local Black community. It is further significant in the areas of Women's History as a rare, identified example in Pueblo of how the 1893 campaign for women's suffrage in Colorado included Black women.